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Diltiazem Malate

CHEMBL1200805 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
548.6 g/mol
LogP
—
Phase
4

A malate salt form of diltiazem, a calcium channel blocker used to treat high blood pressure, angina, and certain heart rhythm disorders. It works by relaxing blood vessels and slowing the heart rate.

الوزن الجزيئي

548,6000 g/mol

TPSA

179,00 Ų

المجالات العلاجية

Cardiovascular Disease Pain Management Gastroesophageal Reflux Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Chronic Pain Hepatitis C Heart Failure Atrial Fibrillation Colorectal Cancer

آلية العمل

Benzothiazepine calcium channel blocker.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Benzothiazepine calcium channel blocker.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1.O=C(O)CC(O)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C22H26N2O4S.C4H6O5/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;5-2(4(8)9)1-3(6)7/h5-12,20-21H,13-14H2,1-4H3;2,5H,1H2,(H,6,7)(H,8,9)/t20-,21+;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C26H32N2O9S

                    

                    
                    

                        
HBD / HBA

                        
3 / 11

                    

                    
                    

                        
الروابط القابلة للدوران

                        
10

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
38

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
A malate salt form of diltiazem, a calcium channel blocker used to treat high blood pressure, angina, and certain heart rhythm disorders. It works by relaxing blood vessels and slowing the heart rate.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Benzothiazepine calcium channel blocker.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Diltiazem Malate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200805.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3037122.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.