Enalapril
This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.
الوزن الجزيئي
376,4470 g/mol
LogP
-0,10
TPSA
95,90 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
تصنيفات الأدوية
آلية العمل
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
InChI
InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
Molecular Formula
C20H28N2O5
HBD / HBA
2 / 6
الروابط القابلة للدوران
10
الذرات الثقيلة
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Key pharmacokinetic parameters for Enalapril: Half-life: 11 hours.
Yes, Enalapril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL578. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5388962. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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