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Fentanyl

CHEMBL596 Phase 4 معتمد Small molecule
Half-Life
2-4 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
336.5 g/mol
LogP
4.0
Phase
4

This is a potent opioid pain reliever that works by binding to opioid receptors in the brain and spinal cord to block pain signals. Due to its high potency, it carries significant risks of dependence and overdose and requires careful medical supervision.

الوزن الجزيئي

336,4700 g/mol

LogP

4,00

TPSA

23,60 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Melanoma Inflammatory Bowel Disease Obstetrics & Gynecology Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

تصنيفات الأدوية

N — N - Nervous System

آلية العمل

Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

Pharmacokinetics (PK)

Half-Life 2-4 hours

Pharmacodynamics (PD)

الآلية

Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

البنية ثنائية الأبعاد

SVG PNG

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SMILES

                    
CCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H28N2O

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
الروابط القابلة للدوران

                        
6

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This is a potent opioid pain reliever that works by binding to opioid receptors in the brain and spinal cord to block pain signals. Due to its high potency, it carries significant risks of dependence and overdose and requires careful medical supervision.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Highly potent synthetic mu-opioid receptor agonist approximately 100 times more potent than morphine.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Fentanyl: Half-life: 2-4 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Fentanyl is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            
            

                
                
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Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
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                            Small molecule
                        
                        
                        
                            Escitalopram
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL596.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3345.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.