Flurazepam Hydrochloride

CHEMBL3989724 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

460.8 g/mol

LogP

—

Phase

4

A hydrochloride salt form of flurazepam, a benzodiazepine used to treat short-term insomnia by enhancing inhibitory signaling in the brain to promote sleep. This salt form improves the drug's solubility for oral administration. Patients should be aware of the risk of tolerance, dependence, and next-day sedation.

الوزن الجزيئي

460,8000 g/mol

TPSA

35,90 Å²

المجالات العلاجية

Schizophrenia Generalized Anxiety Disorder

آلية العمل

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …

البنية ثنائية الأبعاد

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SMILES

CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc21.Cl.Cl

InChI

InChI=1S/C21H23ClFN3O.2ClH/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23;;/h5-10,13H,3-4,11-12,14H2,1-2H3;2*1H

Molecular Formula

C21H25Cl3FN3O

HBD / HBA

2 / 4

الروابط القابلة للدوران

6

الذرات الثقيلة

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A hydrochloride salt form of flurazepam, a benzodiazepine used to treat short-term insomnia by enhancing inhibitory signaling in the brain to promote sleep. This salt form improves the drug's solubility for oral administration. Patients should be aware of the risk of tolerance, dependence, and next-day sedation.

Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.

Yes, Flurazepam Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989724. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 14434. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C21H25Cl3FN3O
المرادفات: 1

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.