Fostemsavir Tromethamine
This tromethamine salt form of fostemsavir is an attachment inhibitor that prevents HIV from binding to and entering human immune cells. It is used as part of combination antiretroviral therapy for adults with multidrug-resistant HIV who have limited treatment options.
الوزن الجزيئي
704,6000 g/mol
TPSA
269,00 Ų
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
COc1cnc(-n2cnc(C)n2)c2c1c(C(=O)C(=O)N1CCN(C(=O)c3ccccc3)CC1)cn2COP(=O)(O)O.NC(CO)(CO)CO
InChI
InChI=1S/C25H26N7O8P.C4H11NO3/c1-16-27-14-32(28-16)23-21-20(19(39-2)12-26-23)18(13-31(21)15-40-41(36,37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17;5-4(1-6,2-7)3-8/h3-7,12-14H,8-11,15H2,1-2H3,(H2,36,37,38);6-8H,1-3,5H2
Molecular Formula
C29H37N8O11P
HBD / HBA
6 / 15
الروابط القابلة للدوران
11
الذرات الثقيلة
49
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This tromethamine salt form of fostemsavir is an attachment inhibitor that prevents HIV from binding to and entering human immune cells. It is used as part of combination antiretroviral therapy for adults with multidrug-resistant HIV who have limited treatment options.
Yes, Fostemsavir Tromethamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3301598. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 46892186. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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