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Gadoxetic Acid

CHEMBL2221312 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
681.7 g/mol
LogP
—
Phase
4

A gadolinium-based contrast agent used in magnetic resonance imaging of the liver, taken up selectively by functional liver cells to provide detailed images of liver structure and detect lesions such as tumors or cirrhosis. It combines the benefits of standard extracellular MRI contrast with liver-specific enhancement during the hepatobiliary phase. It helps physicians distinguish between benign and malignant liver conditions.

الوزن الجزيئي

681,7000 g/mol

TPSA

220,00 Ų

المجالات العلاجية

Pancreatic Cancer Non-Alcoholic Fatty Liver Disease Hypertension Hepatitis C Prostate Cancer Colorectal Cancer

آلية العمل

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
[H+].[H+].CCOC1=CC=C(C=C1)C[C@@H](CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Gd+3]

                

                

                
                

                    
InChI

                    
InChI=1S/C23H33N3O11.Gd/c1-2-37-18-5-3-16(4-6-18)9-17(26(14-22(33)34)15-23(35)36)10-24(11-19(27)28)7-8-25(12-20(29)30)13-21(31)32;/h3-6,17H,2,7-15H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,35,36);/q;+3/p-3/t17-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C23H30GdN3O11

                    

                    
                    

                        
HBD / HBA

                        
2 / 14

                    

                    
                    

                        
الروابط القابلة للدوران

                        
15

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
38

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
A gadolinium-based contrast agent used in magnetic resonance imaging of the liver, taken up selectively by functional liver cells to provide detailed images of liver structure and detect lesions such as tumors or cirrhosis. It combines the benefits of standard extracellular MRI contrast with liver-specific enhancement during the hepatobiliary phase. It helps physicians distinguish between benign and malignant liver conditions.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Gadoxetic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2221312.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 25203894.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.