Guanfacine Hydrochloride

CHEMBL1200494 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

282.5 g/mol

LogP

—

Phase

4

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

الوزن الجزيئي

282,5000 g/mol

TPSA

81,50 Å²

المجالات العلاجية

Pain Management Asthma Schizophrenia Generalized Anxiety Disorder Insomnia Stroke Obesity Hypertension Major Depressive Disorder Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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SMILES

Cl.N=C(N)NC(=O)Cc1c(Cl)cccc1Cl

InChI

InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

Molecular Formula

C9H10Cl3N3O

HBD / HBA

3 / 1

الروابط القابلة للدوران

2

الذرات الثقيلة

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

Yes, Guanfacine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200494. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71401. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C9H10Cl3N3O
المرادفات: 2

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.