Hydralazine Hydrochloride

CHEMBL542541 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

196.6 g/mol

LogP

—

Phase

4

A hydrochloride salt form of hydralazine, a direct arteriolar vasodilator used to treat high blood pressure, heart failure, and hypertensive emergencies in pregnancy such as preeclampsia. The hydrochloride form is used in both oral tablets and injectable formulations for acute blood pressure lowering. Long-term use at high doses requires monitoring for drug-induced lupus-like syndrome.

الوزن الجزيئي

196,6400 g/mol

TPSA

63,80 Å²

المجالات العلاجية

Ovarian Cancer Non-Small Cell Lung Cancer Epilepsy Stroke Type 2 Diabetes Hypertension Breast Cancer Heart Failure Cardiovascular Disease Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

Cl.NNc1nncc2ccccc12

InChI

InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H

Molecular Formula

C8H9ClN4

HBD / HBA

3 / 4

الروابط القابلة للدوران

1

الذرات الثقيلة

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A hydrochloride salt form of hydralazine, a direct arteriolar vasodilator used to treat high blood pressure, heart failure, and hypertensive emergencies in pregnancy such as preeclampsia. The hydrochloride form is used in both oral tablets and injectable formulations for acute blood pressure lowering. Long-term use at high doses requires monitoring for drug-induced lupus-like syndrome.

Yes, Hydralazine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL542541. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9351. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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البنية

بيانات سريعة

الصيغة الجزيئية: C8H9ClN4
المرادفات: 3

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.