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Iodixanol

CHEMBL1200507 Phase 4 معتمد Unknown
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
1550.2 g/mol
LogP
-3.4
Phase
4

This non-ionic, iso-osmolar iodinated contrast agent is used for various diagnostic imaging procedures including cardiovascular angiography, CT scans, and myelography. Its iso-osmolar property minimizes the osmotic stress on blood vessels and kidneys during injection. It carries a lower risk of kidney injury compared to hyperosmolar agents, particularly in patients with pre-existing kidney disease.

الوزن الجزيئي

1550,2000 g/mol

LogP

-3,40

TPSA

339,00 Ų

قاعدة ليبينسكي للخمسة

راسب

المجالات العلاجية

Pancreatic Cancer Cardiovascular Disease Non-Small Cell Lung Cancer Chronic Kidney Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Hyperlipidemia Transplant Medicine

آلية العمل

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)N(CC(O)CN(C(C)=O)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I

                

                

                
                

                    
InChI

                    
InChI=1S/C35H44I6N6O15/c1-13(52)46(30-26(38)20(32(59)42-3-15(54)9-48)24(36)21(27(30)39)33(60)43-4-16(55)10-49)7-19(58)8-47(14(2)53)31-28(40)22(34(61)44-5-17(56)11-50)25(37)23(29(31)41)35(62)45-6-18(57)12-51/h15-19,48-51,54-58H,3-12H2,1-2H3,(H,42,59)(H,43,60)(H,44,61)(H,45,62)

                

                

                

                    
                    

                        
Molecular Formula

                        
C35H44I6N6O15

                    

                    
                    

                        
HBD / HBA

                        
13 / 15

                    

                    
                    

                        
الروابط القابلة للدوران

                        
22

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
62

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This non-ionic, iso-osmolar iodinated contrast agent is used for various diagnostic imaging procedures including cardiovascular angiography, CT scans, and myelography. Its iso-osmolar property minimizes the osmotic stress on blood vessels and kidneys during injection. It carries a lower risk of kidney injury compared to hyperosmolar agents, particularly in patients with pre-existing kidney disease.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Iodixanol is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200507.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3724.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.