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Isoflurane

CHEMBL1256 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
184.5 g/mol
LogP
2.1
Phase
4

This halogenated ether is a widely used inhaled general anesthetic that maintains unconsciousness, muscle relaxation, and analgesia during surgery. It works by modulating multiple ion channels and neurotransmitter systems throughout the central nervous system. It is administered through a vaporizer in a precise concentration calibrated to the patient's needs.

الوزن الجزيئي

184,4900 g/mol

LogP

2,10

TPSA

9,20 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Melanoma Oncology Obstetrics & Gynecology Non-Alcoholic Fatty Liver Disease Stroke Type 2 Diabetes Hypertension Chronic Pain Colorectal Cancer

آلية العمل

Produces reversible loss of consciousness and sensation through modulation of neuronal ion channels and receptor systems in the central nervous system, including GABA-A enhancement and NMDA receptor inhibition.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Produces reversible loss of consciousness and sensation through modulation of neuronal ion channels and receptor systems in the central nervous system, including GABA-A enhancement and NMDA receptor inhibition.

البنية ثنائية الأبعاد

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Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
FC(F)OC(Cl)C(F)(F)F

                

                

                
                

                    
InChI

                    
InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H

                

                

                

                    
                    

                        
Molecular Formula

                        
C3H2ClF5O

                    

                    
                    

                        
HBD / HBA

                        
- / 6

                    

                    
                    

                        
الروابط القابلة للدوران

                        
2

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
10

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This halogenated ether is a widely used inhaled general anesthetic that maintains unconsciousness, muscle relaxation, and analgesia during surgery. It works by modulating multiple ion channels and neurotransmitter systems throughout the central nervous system. It is administered through a vaporizer in a precise concentration calibrated to the patient's needs.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Produces reversible loss of consciousness and sensation through modulation of neuronal ion channels and receptor systems in the central nervous system, including GABA-A enhancement and NMDA receptor inhibition.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Isoflurane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1256.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3763.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.