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Isoniazid

CHEMBL64 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
137.1 g/mol
LogP
-0.7
Phase
4

This first-line antibiotic is used to treat and prevent tuberculosis (TB) by inhibiting mycolic acid synthesis, a key component of the mycobacterial cell wall. It is one of the most important TB drugs and is used in combination with other agents to prevent the development of resistance. Long-term use requires supplementation with vitamin B6 (pyridoxine) to prevent peripheral neuropathy.

الوزن الجزيئي

137,1400 g/mol

LogP

-0,70

TPSA

68,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Melanoma Asthma Chronic Obstructive Pulmonary Disease Systemic Lupus Erythematosus Deep Vein Thrombosis / Pulmonary Embolism Type 2 Diabetes Hypertension Malaria HIV/AIDS Hepatitis C Tuberculosis

آلية العمل

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
NNC(=O)c1ccncc1

                

                

                
                

                    
InChI

                    
InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)

                

                

                

                    
                    

                        
Molecular Formula

                        
C6H7N3O

                    

                    
                    

                        
HBD / HBA

                        
2 / 3

                    

                    
                    

                        
الروابط القابلة للدوران

                        
1

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
10

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This first-line antibiotic is used to treat and prevent tuberculosis (TB) by inhibiting mycolic acid synthesis, a key component of the mycobacterial cell wall. It is one of the most important TB drugs and is used in combination with other agents to prevent the development of resistance. Long-term use requires supplementation with vitamin B6 (pyridoxine) to prevent peripheral neuropathy.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Isoniazid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL64.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3767.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.