Isoproterenol Hydrochloride

CHEMBL1711 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
247.7 g/mol
LogP
Phase
4

This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.

الوزن الجزيئي

247,7200 g/mol

TPSA

72,70 Ų

المجالات العلاجية

آلية العمل

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

البنية ثنائية الأبعاد

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SMILES

CC(C)NCC(O)c1ccc(O)c(O)c1.Cl

InChI

InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

Molecular Formula

C11H18ClNO3

HBD / HBA

5 / 4

الروابط القابلة للدوران

4

الذرات الثقيلة

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Yes, Isoproterenol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1711. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5807. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.