Isoproterenol Hydrochloride
This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.
الوزن الجزيئي
247,7200 g/mol
TPSA
72,70 Ų
المجالات العلاجية
آلية العمل
Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1.Cl
InChI
InChI=1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
Molecular Formula
C11H18ClNO3
HBD / HBA
5 / 4
الروابط القابلة للدوران
4
الذرات الثقيلة
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This hydrochloride salt of isoproterenol is the standard injectable form used in acute care settings for cardiac emergencies such as symptomatic bradycardia and heart block while awaiting pacemaker placement. It also has bronchodilatory properties and has historically been used for asthma. Its potent cardiac effects require continuous monitoring during use.
Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.
Yes, Isoproterenol Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1711. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5807. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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