Maraviroc
A CCR5 antagonist antiretroviral medication used in combination with other HIV drugs to treat adults infected with CCR5-tropic HIV-1 by blocking the receptor the virus uses to enter immune cells. It requires a specific blood test to confirm the virus uses the CCR5 receptor before use.
الوزن الجزيئي
513,7000 g/mol
LogP
5,10
TPSA
63,10 Ų
قاعدة ليبينسكي للخمسة
راسب
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
Cc1nnc(C(C)C)n1[C@H]1C[C@H]2CC[C@@H](C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1
InChI
InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25+,26-/m0/s1
Molecular Formula
C29H41F2N5O
HBD / HBA
1 / 6
الروابط القابلة للدوران
8
الذرات الثقيلة
37
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
A CCR5 antagonist antiretroviral medication used in combination with other HIV drugs to treat adults infected with CCR5-tropic HIV-1 by blocking the receptor the virus uses to enter immune cells. It requires a specific blood test to confirm the virus uses the CCR5 receptor before use.
Yes, Maraviroc is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL256907. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3002977. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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