Mephenytoin
An anticonvulsant related to phenytoin used to control certain types of seizures in patients who have not responded to safer first-line antiepileptic drugs. It carries a higher risk of serious side effects compared to other seizure medications and is rarely used today.
الوزن الجزيئي
218,2500 g/mol
LogP
1,50
TPSA
49,40 Ų
قاعدة ليبينسكي للخمسة
ناجح
آلية العمل
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of …
البنية ثنائية الأبعاد
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SMILES
CCC1(c2ccccc2)NC(=O)N(C)C1=O
InChI
InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)
Molecular Formula
C12H14N2O2
HBD / HBA
1 / 2
الروابط القابلة للدوران
2
الذرات الثقيلة
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
An anticonvulsant related to phenytoin used to control certain types of seizures in patients who have not responded to safer first-line antiepileptic drugs. It carries a higher risk of serious side effects compared to other seizure medications and is rarely used today.
Modulates neuronal excitability through one or more mechanisms including blockade of voltage-gated sodium channels, enhancement of GABAergic inhibition, or modulation of calcium channels. This reduces the frequency and severity of seizure activity.
Yes, Mephenytoin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL861. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4060. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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