Metamizole

CHEMBL461522 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

311.4 g/mol

LogP

—

Phase

4

A non-opioid analgesic for severe pain, with rare agranulocytosis risk.

الوزن الجزيئي

311,3600 g/mol

LogP

0,00

TPSA

89,50 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pain Management Migraine Generalized Anxiety Disorder Infectious Disease Non-Alcoholic Fatty Liver Disease Stroke Obesity Gastroenterology Hypertension Chronic Pain

آلية العمل

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

البنية ثنائية الأبعاد

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SMILES

Cc1c(N(C)CS(=O)(=O)O)c(=O)n(-c2ccccc2)n1C

InChI

InChI=1S/C13H17N3O4S/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11/h4-8H,9H2,1-3H3,(H,18,19,20)

Molecular Formula

C13H17N3O4S

HBD / HBA

1 / 6

الروابط القابلة للدوران

4

الذرات الثقيلة

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A non-opioid analgesic for severe pain, with rare agranulocytosis risk.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Metamizole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL461522. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3111. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C13H17N3O4S
المرادفات: 2

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.