Metocurine Iodide
A nondepolarizing neuromuscular blocking agent used during surgery and mechanical ventilation to relax skeletal muscles and facilitate intubation. It works by competitively blocking acetylcholine at the neuromuscular junction, preventing muscle contraction.
الوزن الجزيئي
906,6000 g/mol
TPSA
55,40 Ų
آلية العمل
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
COc1ccc2cc1Oc1cc3c(cc1OC)CC[N+](C)(C)[C@H]3Cc1ccc(cc1)Oc1c(OC)c(OC)cc3c1[C@@H](C2)[N+](C)(C)CC3.[I-].[I-]
InChI
InChI=1S/C40H48N2O6.2HI/c1-41(2)17-15-27-22-34(44-6)36-24-30(27)31(41)19-25-9-12-29(13-10-25)47-40-38-28(23-37(45-7)39(40)46-8)16-18-42(3,4)32(38)20-26-11-14-33(43-5)35(21-26)48-36;;/h9-14,21-24,31-32H,15-20H2,1-8H3;2*1H/q+2;;/p-2/t31-,32+;;/m0../s1
Molecular Formula
C40H48I2N2O6
HBD / HBA
- / 8
الروابط القابلة للدوران
4
الذرات الثقيلة
50
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
A nondepolarizing neuromuscular blocking agent used during surgery and mechanical ventilation to relax skeletal muscles and facilitate intubation. It works by competitively blocking acetylcholine at the neuromuscular junction, preventing muscle contraction.
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Yes, Metocurine Iodide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1739. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24244. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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