Nabumetone
This non-steroidal anti-inflammatory drug (NSAID) is used to relieve pain, swelling, and stiffness caused by arthritis. It works by blocking enzymes that produce inflammatory chemicals in the body, and it is taken once or twice daily with food to reduce stomach upset.
الوزن الجزيئي
228,2900 g/mol
LogP
3,10
TPSA
26,30 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
آلية العمل
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
COc1ccc2cc(CCC(C)=O)ccc2c1
InChI
InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3
Molecular Formula
C15H16O2
HBD / HBA
- / 2
الروابط القابلة للدوران
4
الذرات الثقيلة
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This non-steroidal anti-inflammatory drug (NSAID) is used to relieve pain, swelling, and stiffness caused by arthritis. It works by blocking enzymes that produce inflammatory chemicals in the body, and it is taken once or twice daily with food to reduce stomach upset.
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.
Yes, Nabumetone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1070. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4409. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="nabumetone"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/nabumetone/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/nabumetone/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/nabumetone/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="nabumetone"></drugfyi-drug>