Nafcillin

CHEMBL1443 Phase 4 معتمد Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
414.5 g/mol
LogP
2.9
Phase
4

This penicillin-type antibiotic is used to treat serious bacterial infections caused by staphylococci, including those resistant to other penicillins. It is typically given by injection in a hospital setting and works by disrupting the bacteria's ability to build their cell walls.

الوزن الجزيئي

414,5000 g/mol

LogP

2,90

TPSA

121,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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SMILES

CCOc1ccc2ccccc2c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O

InChI

InChI=1S/C21H22N2O5S/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27)/t15-,16+,19-/m1/s1

Molecular Formula

C21H22N2O5S

HBD / HBA

2 / 6

الروابط القابلة للدوران

5

الذرات الثقيلة

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

This penicillin-type antibiotic is used to treat serious bacterial infections caused by staphylococci, including those resistant to other penicillins. It is typically given by injection in a hospital setting and works by disrupting the bacteria's ability to build their cell walls.

Yes, Nafcillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1443. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 8982. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.