Natalizumab

CHEMBL1201607 Phase 4 معتمد Antibody
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

This monoclonal antibody is given by intravenous infusion to treat relapsing forms of multiple sclerosis and moderate to severe Crohn's disease. It works by preventing immune cells from crossing into the brain, spinal cord, or gut lining, where they would otherwise cause damaging inflammation.

المجالات العلاجية

آلية العمل

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

This monoclonal antibody is given by intravenous infusion to treat relapsing forms of multiple sclerosis and moderate to severe Crohn's disease. It works by preventing immune cells from crossing into the brain, spinal cord, or gut lining, where they would otherwise cause damaging inflammation.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Natalizumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201607. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.