Peficitinib

CHEMBL3137308 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

326.4 g/mol

LogP

1.9

Phase

4

A JAK inhibitor taken orally to treat rheumatoid arthritis by blocking the signaling pathways that drive joint inflammation and damage. It provides an oral alternative to injectable biologic therapies for patients who need disease-modifying treatment.

الوزن الجزيئي

326,4000 g/mol

LogP

1,90

TPSA

104,00 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Rheumatoid Arthritis Psoriasis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

NC(=O)c1cnc2[nH]ccc2c1N[C@@H]1[C@@H]2CC3C[C@H]1C[C@@](O)(C3)C2

InChI

InChI=1S/C18H22N4O2/c19-16(23)13-8-21-17-12(1-2-20-17)15(13)22-14-10-3-9-4-11(14)7-18(24,5-9)6-10/h1-2,8-11,14,24H,3-7H2,(H2,19,23)(H2,20,21,22)/t9?,10-,11+,14-,18-

Molecular Formula

C18H22N4O2

HBD / HBA

4 / 4

الروابط القابلة للدوران

3

الذرات الثقيلة

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A JAK inhibitor taken orally to treat rheumatoid arthritis by blocking the signaling pathways that drive joint inflammation and damage. It provides an oral alternative to injectable biologic therapies for patients who need disease-modifying treatment.

Yes, Peficitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3137308. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 57928403. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C18H22N4O2

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.