Prazosin

CHEMBL2 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

383.4 g/mol

LogP

2.0

Phase

4

Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder. It can cause dizziness when standing up, especially with the first dose.

الوزن الجزيئي

383,4000 g/mol

LogP

2,00

TPSA

107,00 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Benign Prostatic Hyperplasia Cardiovascular Disease Respiratory Disease Pain Management Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Migraine Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hypertension Chronic Pain Hepatitis C Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC

InChI

InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)

Molecular Formula

C19H21N5O4

HBD / HBA

1 / 8

الروابط القابلة للدوران

4

الذرات الثقيلة

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder. It can cause dizziness when standing up, especially with the first dose.

Yes, Prazosin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4893. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C19H21N5O4
المرادفات: 1

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.