Pyrilamine
Pyrilamine is a first-generation antihistamine of the ethylenediamine class that competitively antagonizes histamine H1 receptors, reducing allergic symptoms including rhinorrhea, sneezing, and pruritus, and also possesses significant anticholinergic and sedative properties. It is used in combination over-the-counter products for allergy, cold, and sleep aid formulations.
الوزن الجزيئي
285,4000 g/mol
LogP
3,30
TPSA
28,60 Ų
قاعدة ليبينسكي للخمسة
ناجح
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
COc1ccc(CN(CCN(C)C)c2ccccn2)cc1
InChI
InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
Molecular Formula
C17H23N3O
HBD / HBA
- / 4
الروابط القابلة للدوران
7
الذرات الثقيلة
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
Pyrilamine is a first-generation antihistamine of the ethylenediamine class that competitively antagonizes histamine H1 receptors, reducing allergic symptoms including rhinorrhea, sneezing, and pruritus, and also possesses significant anticholinergic and sedative properties. It is used in combination over-the-counter products for allergy, cold, and sleep aid formulations.
Yes, Pyrilamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL511. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4992. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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