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Pyritinol

CHEMBL488093 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
368.5 g/mol
LogP
1.2
Phase
4

Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.

الوزن الجزيئي

368,5000 g/mol

LogP

1,20

TPSA

157,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Schizophrenia Generalized Anxiety Disorder

آلية العمل

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Cc1ncc(CSSCc2cnc(C)c(O)c2CO)c(CO)c1O

                

                

                
                

                    
InChI

                    
InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H20N2O4S2

                    

                    
                    

                        
HBD / HBA

                        
4 / 8

                    

                    
                    

                        
الروابط القابلة للدوران

                        
7

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
Pyritinol is a semi-synthetic derivative of pyridoxine (vitamin B6) that is believed to enhance cholinergic neurotransmission and cerebral glucose metabolism, and has been used as a nootropic and neuroprotective agent. It was used for the treatment of cognitive impairment and has been investigated in anxiety disorders, schizophrenia, and rheumatoid arthritis, though it was withdrawn in some countries due to rare but serious adverse effects.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Pyritinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL488093.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 14190.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.