Romidepsin
A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.
الوزن الجزيئي
540,7000 g/mol
LogP
2,20
TPSA
193,00 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O
InChI
InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1
Molecular Formula
C24H36N4O6S2
HBD / HBA
4 / 8
الروابط القابلة للدوران
2
الذرات الثقيلة
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.
Yes, Romidepsin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL343448. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5352062. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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