Romidepsin

CHEMBL343448 Phase 4 معتمد Protein
Half-Life
Bioavailability
Protein Binding
Molecular Weight
540.7 g/mol
LogP
2.2
Phase
4

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

الوزن الجزيئي

540,7000 g/mol

LogP

2,20

TPSA

193,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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SMILES

C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O

InChI

InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1

Molecular Formula

C24H36N4O6S2

HBD / HBA

4 / 8

الروابط القابلة للدوران

2

الذرات الثقيلة

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

Yes, Romidepsin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL343448. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5352062. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.