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Rosuvastatin Calcium

CHEMBL1744447 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
1001.1 g/mol
LogP
—
Phase
4

The calcium salt formulation of rosuvastatin used to treat high cholesterol and reduce cardiovascular risk in adults and certain children with inherited cholesterol disorders. Once-daily dosing and availability in multiple strengths allows for flexible treatment individualization.

الوزن الجزيئي

1001,1000 g/mol

TPSA

304,00 Ų

المجالات العلاجية

Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Glaucoma Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Parkinson's Disease Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Chronic Kidney Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Hyperlipidemia Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Malaria HIV/AIDS Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Cardiovascular Disease Prostate Cancer Colorectal Cancer Leukemia

آلية العمل

Competitive inhibitor of HMG-CoA reductase.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Competitive inhibitor of HMG-CoA reductase.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-].CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-].[Ca+2]

                

                

                
                

                    
InChI

                    
InChI=1S/2C22H28FN3O6S.Ca/c2*1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h2*5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b2*10-9+;/t2*16-,17-;/m11./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C44H54CaF2N6O12S2

                    

                    
                    

                        
HBD / HBA

                        
4 / 20

                    

                    
                    

                        
الروابط القابلة للدوران

                        
18

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
67

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
The calcium salt formulation of rosuvastatin used to treat high cholesterol and reduce cardiovascular risk in adults and certain children with inherited cholesterol disorders. Once-daily dosing and availability in multiple strengths allows for flexible treatment individualization.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Competitive inhibitor of HMG-CoA reductase.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Rosuvastatin Calcium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1744447.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5282455.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.