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Seratrodast

CHEMBL70972 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
354.4 g/mol
LogP
4.4
Phase
4

Seratrodast is a thromboxane A2 receptor antagonist used for the treatment of asthma in Japan and some Asian countries, where it reduces bronchoconstriction and airway inflammation mediated by thromboxane A2. By blocking thromboxane A2 prostanoid (TP) receptors on airway smooth muscle and inflammatory cells, it inhibits bronchoconstriction, platelet aggregation, and inflammatory cell recruitment. It provides anti-asthmatic effects without the direct bronchodilatory action of beta-agonists.

الوزن الجزيئي

354,4000 g/mol

LogP

4,40

TPSA

71,40 Ų

قاعدة ليبينسكي للخمسة

ناجح

آلية العمل

Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC1=C(C)C(=O)C(C(CCCCCC(=O)O)c2ccccc2)=C(C)C1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C22H26O4/c1-14-15(2)22(26)20(16(3)21(14)25)18(17-10-6-4-7-11-17)12-8-5-9-13-19(23)24/h4,6-7,10-11,18H,5,8-9,12-13H2,1-3H3,(H,23,24)

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H26O4

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
الروابط القابلة للدوران

                        
8

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
Seratrodast is a thromboxane A2 receptor antagonist used for the treatment of asthma in Japan and some Asian countries, where it reduces bronchoconstriction and airway inflammation mediated by thromboxane A2. By blocking thromboxane A2 prostanoid (TP) receptors on airway smooth muscle and inflammatory cells, it inhibits bronchoconstriction, platelet aggregation, and inflammatory cell recruitment. It provides anti-asthmatic effects without the direct bronchodilatory action of beta-agonists.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Seratrodast is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL70972.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2449.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.