Sorafenib Tosylate

CHEMBL1200485 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

637.0 g/mol

LogP

—

Phase

4

A tosylate salt form of sorafenib with the same therapeutic properties. This multi-targeted oral kinase inhibitor blocks several proteins that cancer cells use to grow new blood vessels and divide, effectively cutting off tumor blood supply and directly slowing cancer cell proliferation.

الوزن الجزيئي

637,0000 g/mol

TPSA

155,00 Å²

المجالات العلاجية

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Respiratory Disease Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Infectious Disease Melanoma Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Lymphoma Breast Cancer Hepatitis C Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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SMILES

CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1.Cc1ccc(S(=O)(=O)O)cc1

InChI

InChI=1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10)

Molecular Formula

C28H24ClF3N4O6S

HBD / HBA

4 / 10

الروابط القابلة للدوران

6

الذرات الثقيلة

43

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

A tosylate salt form of sorafenib with the same therapeutic properties. This multi-targeted oral kinase inhibitor blocks several proteins that cancer cells use to grow new blood vessels and divide, effectively cutting off tumor blood supply and directly slowing cancer cell proliferation.

Yes, Sorafenib Tosylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200485. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 406563. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C28H24ClF3N4O6S

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.