Sulfamethoxazole

CHEMBL443 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

253.3 g/mol

LogP

0.9

Phase

4

Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.

الوزن الجزيئي

253,2800 g/mol

LogP

0,90

TPSA

107,00 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Infectious Disease Bladder Cancer Benign Prostatic Hyperplasia Age-Related Macular Degeneration Hematology Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Systemic Lupus Erythematosus Chronic Kidney Disease Stroke Obesity Lymphoma Breast Cancer Atopic Dermatitis Malaria HIV/AIDS Tuberculosis Prostate Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

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SMILES

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

Molecular Formula

C10H11N3O3S

HBD / HBA

2 / 6

الروابط القابلة للدوران

3

الذرات الثقيلة

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.

Yes, Sulfamethoxazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL443. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5329. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C10H11N3O3S
المرادفات: 6

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.