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Tadalafil

CHEMBL779 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
389.4 g/mol
LogP
2.3
Phase
4

This medication relaxes the muscles and blood vessels in the penis to help men achieve and maintain an erection, and is also used to treat the symptoms of an enlarged prostate. In addition, it is prescribed to lower blood pressure in the lungs (pulmonary arterial hypertension), allowing patients to exercise more easily. It should not be taken with nitrate medications due to the risk of a dangerous drop in blood pressure.

الوزن الجزيئي

389,4000 g/mol

LogP

2,30

TPSA

74,90 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Parkinson's Disease Stroke Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H19N3O4

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
الروابط القابلة للدوران

                        
1

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This medication relaxes the muscles and blood vessels in the penis to help men achieve and maintain an erection, and is also used to treat the symptoms of an enlarged prostate. In addition, it is prescribed to lower blood pressure in the lungs (pulmonary arterial hypertension), allowing patients to exercise more easily. It should not be taken with nitrate medications due to the risk of a dangerous drop in blood pressure.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Tadalafil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL779.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 110635.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.