Taurursodiol

CHEMBL272427 Phase 4 معتمد Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

499.7 g/mol

LogP

3.6

Phase

4

Taurursodiol (sodium phenylbutyrate/ursodoxicoltaurine, also known as AMX0035) is a fixed-dose combination product that modulates endoplasmic reticulum stress and mitochondrial dysfunction, reducing neuronal and motor neuron apoptosis. It is approved for the treatment of amyotrophic lateral sclerosis (ALS) and is under investigation for neurodegenerative diseases. By targeting two complementary pathways of cell death, it offers a novel approach to neuroprotection.

الوزن الجزيئي

499,7000 g/mol

LogP

3,60

TPSA

132,00 Å²

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

Asthma Multiple Sclerosis Obesity Type 2 Diabetes Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

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Embed this structure

SMILES

C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1

Molecular Formula

C26H45NO6S

HBD / HBA

4 / 6

الروابط القابلة للدوران

7

الذرات الثقيلة

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Taurursodiol (sodium phenylbutyrate/ursodoxicoltaurine, also known as AMX0035) is a fixed-dose combination product that modulates endoplasmic reticulum stress and mitochondrial dysfunction, reducing neuronal and motor neuron apoptosis. It is approved for the treatment of amyotrophic lateral sclerosis (ALS) and is under investigation for neurodegenerative diseases. By targeting two complementary pathways of cell death, it offers a novel approach to neuroprotection.

Yes, Taurursodiol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL272427. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9848818. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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البنية

بيانات سريعة

الصيغة الجزيئية: C26H45NO6S

روابط خارجية

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إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.