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Technetium Tc 99M Fanolesomab

CHEMBL2107902 Phase 4 معتمد Antibody
Half-Life
—
Bioavailability
—
Protein Binding
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Molecular Weight
— g/mol
LogP
—
Phase
4

Technetium Tc 99m fanolesomab is a radiolabeled murine anti-CD15 monoclonal antibody that targets CD15 (3-fucosyl-N-acetyl-lactosamine) expressed on activated neutrophils and other granulocytes, enabling scintigraphic imaging of infection and inflammation sites. It was developed for the diagnosis of appendicitis and osteomyelitis by detecting sites of neutrophil accumulation. Its use has been limited by adverse reactions associated with the murine antibody.

آلية العمل

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Technetium Tc 99m fanolesomab is a radiolabeled murine anti-CD15 monoclonal antibody that targets CD15 (3-fucosyl-N-acetyl-lactosamine) expressed on activated neutrophils and other granulocytes, enabling scintigraphic imaging of infection and inflammation sites. It was developed for the diagnosis of appendicitis and osteomyelitis by detecting sites of neutrophil accumulation. Its use has been limited by adverse reactions associated with the murine antibody.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Technetium Tc 99M Fanolesomab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107902. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.