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Technetium Tc 99M Mebrofenin

CHEMBL1200421 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
869.3 g/mol
LogP
—
Phase
4

Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.

الوزن الجزيئي

869,3000 g/mol

TPSA

225,00 Ų

آلية العمل

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

SMILES

CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.[99Tc+4]

InChI

InChI=1S/2C15H19BrN2O5.Tc/c2*1-8-4-9(2)15(10(3)14(8)16)17-11(19)5-18(6-12(20)21)7-13(22)23;/h2*4H,5-7H2,1-3H3,(H,17,19)(H,20,21)(H,22,23);/q;;+4/p-4/i;;1+1

Molecular Formula

C30H34Br2N4O10Tc

HBD / HBA

2 / 12

الروابط القابلة للدوران

10

الذرات الثقيلة

47

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.

Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.

Yes, Technetium Tc 99M Mebrofenin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200421. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 172866200. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.