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Technetium Tc 99M Pentetate

CHEMBL2096656 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
487.2 g/mol
LogP
—
Phase
4

Technetium Tc 99m pentetate (99mTc-DTPA) is a versatile radiopharmaceutical used for GFR measurement, renal dynamic scintigraphy, lung ventilation aerosol imaging, and brain imaging for blood-brain barrier disruption. See technetium-pentetate for complete pharmacological details. Its purely glomerular filtration without tubular involvement makes it the reference standard for GFR measurement.

الوزن الجزيئي

487,2100 g/mol

TPSA

210,00 Ų

المجالات العلاجية

Melanoma Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Rheumatoid Arthritis Breast Cancer Prostate Cancer Colorectal Cancer

آلية العمل

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

الآلية

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

SMILES

C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[99Tc+4]

InChI

InChI=1S/C14H23N3O10.Tc/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);/q;+4/p-5/i;1+1

Molecular Formula

C14H18N3O10Tc-

HBD / HBA

- / 13

الروابط القابلة للدوران

11

الذرات الثقيلة

28

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

الأسئلة الشائعة

Technetium Tc 99m pentetate (99mTc-DTPA) is a versatile radiopharmaceutical used for GFR measurement, renal dynamic scintigraphy, lung ventilation aerosol imaging, and brain imaging for blood-brain barrier disruption. See technetium-pentetate for complete pharmacological details. Its purely glomerular filtration without tubular involvement makes it the reference standard for GFR measurement.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Technetium Tc 99M Pentetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2096656. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 166744. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

إخلاء المسؤولية الطبية

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.