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Telaprevir

CHEMBL231813 Phase 4 معتمد Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
679.8 g/mol
LogP
4.2
Phase
4

This antiviral medication was used as part of combination therapy to treat chronic hepatitis C infection caused by genotype 1 of the virus. It works by blocking an enzyme (protease) that the hepatitis C virus needs to replicate. It has largely been replaced by newer, better-tolerated hepatitis C treatments.

الوزن الجزيئي

679,8000 g/mol

LogP

4,20

TPSA

180,00 Ų

قاعدة ليبينسكي للخمسة

ناجح

المجالات العلاجية

HIV/AIDS Hepatitis C

Pharmacokinetics (PK)

Pharmacodynamics (PD)

البنية ثنائية الأبعاد

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25-,27-,28-,30+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C36H53N7O6

                    

                    
                    

                        
HBD / HBA

                        
4 / 8

                    

                    
                    

                        
الروابط القابلة للدوران

                        
14

                    

                    
                    
                    

                        
الذرات الثقيلة

                        
49

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
الأسئلة الشائعة

                

                    
                    

                        
                        

                            
This antiviral medication was used as part of combination therapy to treat chronic hepatitis C infection caused by genotype 1 of the virus. It works by blocking an enzyme (protease) that the hepatitis C virus needs to replicate. It has largely been replaced by newer, better-tolerated hepatitis C treatments.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Telaprevir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL231813.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3010818.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
إخلاء المسؤولية الطبية

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.