Tilbroquinol
Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.
الوزن الجزيئي
238,0800 g/mol
LogP
3,10
TPSA
33,10 Ų
قاعدة ليبينسكي للخمسة
ناجح
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
Cc1cc(Br)c(O)c2ncccc12
InChI
InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3
Molecular Formula
C10H8BrNO
HBD / HBA
1 / 2
الروابط القابلة للدوران
0
الذرات الثقيلة
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.
Yes, Tilbroquinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1788385. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 65592. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="tilbroquinol"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/tilbroquinol/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/tilbroquinol/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/tilbroquinol/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="tilbroquinol"></drugfyi-drug>