Ziprasidone
This atypical antipsychotic medication is used to treat schizophrenia and bipolar mania, working by blocking dopamine and serotonin receptors in the brain to reduce symptoms such as hallucinations, delusions, and mood instability. It can prolong the QT interval on an electrocardiogram, so a baseline heart tracing is recommended before starting, and it should not be combined with other drugs that have the same effect. It should be taken with food to ensure adequate absorption.
الوزن الجزيئي
412,9000 g/mol
LogP
4,00
TPSA
76,70 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1
InChI
InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)
Molecular Formula
C21H21ClN4OS
HBD / HBA
1 / 5
الروابط القابلة للدوران
4
الذرات الثقيلة
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This atypical antipsychotic medication is used to treat schizophrenia and bipolar mania, working by blocking dopamine and serotonin receptors in the brain to reduce symptoms such as hallucinations, delusions, and mood instability. It can prolong the QT interval on an electrocardiogram, so a baseline heart tracing is recommended before starting, and it should not be combined with other drugs that have the same effect. It should be taken with food to ensure adequate absorption.
Yes, Ziprasidone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL708. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60854. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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