Zonisamide
This anticonvulsant medication is used as an add-on treatment for partial seizures in adults with epilepsy and is also used off-label as an adjunct in Parkinson's disease. It works through multiple mechanisms including blocking sodium and calcium channels in the brain to reduce abnormal electrical activity. It can cause kidney stones, so adequate hydration is important, and it should be avoided in patients with sulfonamide allergies.
الوزن الجزيئي
212,2300 g/mol
LogP
0,20
TPSA
94,60 Ų
قاعدة ليبينسكي للخمسة
ناجح
المجالات العلاجية
Pharmacokinetics (PK)
Pharmacodynamics (PD)
البنية ثنائية الأبعاد
Cite this structure
Embed this structure
SMILES
NS(=O)(=O)Cc1noc2ccccc12
InChI
InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
Molecular Formula
C8H8N2O3S
HBD / HBA
1 / 5
الروابط القابلة للدوران
2
الذرات الثقيلة
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
الأسئلة الشائعة
This anticonvulsant medication is used as an add-on treatment for partial seizures in adults with epilepsy and is also used off-label as an adjunct in Parkinson's disease. It works through multiple mechanisms including blocking sodium and calcium channels in the brain to reduce abnormal electrical activity. It can cause kidney stones, so adequate hydration is important, and it should be avoided in patients with sulfonamide allergies.
Yes, Zonisamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL750. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5734. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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