PDCD1 (Programmed Cell Death Protein 1)
PDCD1
Immune checkpoint receptor on T cells that suppresses anti-tumor immunity.
الوظيفة
PD-1 inhibitors (pembrolizumab, nivolumab) reactivate exhausted T cells against tumors.
الأدوية التي تؤثر على هذا الهدف
| الدواء | الفعل | أساسي |
|---|---|---|
| Pembrolizumab | Antagonist | نعم |
Related Targets
OPRM1 (Mu-Opioid Receptor)
OPRM1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2