Acetaminophen vs Duloxetine

## Acetaminophen vs Duloxetine: Overview

This comparison examines the pharmacological differences between **Acetaminophen** and **Duloxetine**.

## Mechanism of Action

**Acetaminophen**: Inhibits prostaglandin synthesis in the CNS and peripherally blocks pain impulse generation.

**Duloxetine**: Serotonin-norepinephrine reuptake inhibitor (SNRI).

## Pharmacokinetics

**Half-life**: Acetaminophen — 1-4 hours; Duloxetine — 12 hours.

## Chemical Properties

**Molecular Formula**: Acetaminophen — C8H9NO2; Duloxetine — C18H19NOS.

**Molecular Weight**: Acetaminophen — 151.1630 g/mol; Duloxetine — 297.4150 g/mol.

**Type**: Acetaminophen — Small molecule; Duloxetine — Small molecule.