Amoxicillin vs Trimethoprim

## Amoxicillin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Amoxicillin** and **Trimethoprim**.

## Mechanism of Action

**Amoxicillin**: Inhibits bacterial cell wall synthesis by binding to PBPs.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Amoxicillin — 1-1.5 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Amoxicillin — C16H19N3O5S; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Amoxicillin — 365.4050 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Amoxicillin — Small molecule; Trimethoprim — Small molecule.