Aspirin vs Celecoxib

## Aspirin vs Celecoxib: Overview

This comparison examines the pharmacological differences between **Aspirin** and **Celecoxib**.

## Mechanism of Action

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

**Celecoxib**: Selective COX-2 inhibitor.

## Pharmacokinetics

**Half-life**: Aspirin — 2-3 hours; Celecoxib — 11 hours.

## Chemical Properties

**Molecular Formula**: Aspirin — C9H8O4; Celecoxib — C17H14F3N3O2S.

**Molecular Weight**: Aspirin — 180.1580 g/mol; Celecoxib — 381.3730 g/mol.

**Type**: Aspirin — Small molecule; Celecoxib — Small molecule.