Atezolizumab vs Trastuzumab

## Atezolizumab vs Trastuzumab: Overview

This comparison examines the pharmacological differences between **Atezolizumab** and **Trastuzumab**.

## Mechanism of Action

**Atezolizumab**: Fully human anti-PD-L1 IgG1 monoclonal antibody blocking PD-L1 interaction with PD-1 and B7.1.

**Trastuzumab**: Anti-HER2 monoclonal antibody inhibiting receptor signaling.

## Pharmacokinetics

**Half-life**: Atezolizumab — 27 days; Trastuzumab — 28 days.

## Chemical Properties

**Type**: Atezolizumab — Antibody; Trastuzumab — Antibody.