Buprenorphine vs Citalopram

## Buprenorphine vs Citalopram: Overview

This comparison examines the pharmacological differences between **Buprenorphine** and **Citalopram**.

## Mechanism of Action

**Buprenorphine**: Partial mu-opioid receptor agonist and kappa antagonist with high receptor affinity.

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

## Pharmacokinetics

**Half-life**: Buprenorphine — 24-42 hours; Citalopram — 35 hours.

## Chemical Properties

**Molecular Formula**: Buprenorphine — C29H41NO4; Citalopram — C20H21FN2O.

**Molecular Weight**: Buprenorphine — 467.6430 g/mol; Citalopram — 324.3920 g/mol.

**Type**: Buprenorphine — Small molecule; Citalopram — Small molecule.