Bupropion vs Trazodone

Bupropion vs Trazodone: Overview

This comparison examines the pharmacological differences between Bupropion and Trazodone.

Mechanism of Action

Bupropion: Norepinephrine-dopamine reuptake inhibitor (NDRI).

Trazodone: Serotonin antagonist and reuptake inhibitor (SARI).

Pharmacokinetics

Half-life: Bupropion — 21 hours; Trazodone — 5-9 hours.

Chemical Properties

Molecular Formula: Bupropion — C13H18ClNO; Trazodone — C19H22ClN5O.

Molecular Weight: Bupropion — 239.7420 g/mol; Trazodone — 371.8640 g/mol.

Type: Bupropion — Small molecule; Trazodone — Small molecule.