Candesartan vs Lisinopril

Candesartan vs Lisinopril: Overview

This comparison examines the pharmacological differences between Candesartan and Lisinopril.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Lisinopril: ACE inhibitor preventing conversion of angiotensin I to angiotensin II.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Lisinopril — 12 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Lisinopril — C21H31N3O5.

Molecular Weight: Candesartan — 610.6640 g/mol; Lisinopril — 405.4900 g/mol.

Type: Candesartan — Small molecule; Lisinopril — Small molecule.