Candesartan vs Sildenafil

Candesartan vs Sildenafil: Overview

This comparison examines the pharmacological differences between Candesartan and Sildenafil.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Sildenafil: Selective PDE5 inhibitor increasing cGMP.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Sildenafil — 4 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Sildenafil — C22H30N6O4S.

Molecular Weight: Candesartan — 610.6640 g/mol; Sildenafil — 474.5800 g/mol.

Type: Candesartan — Small molecule; Sildenafil — Small molecule.