Candesartan vs Valsartan

Candesartan vs Valsartan: Overview

This comparison examines the pharmacological differences between Candesartan and Valsartan.

Mechanism of Action

Candesartan: Prodrug hydrolyzed to active form; selective angiotensin II type 1 receptor blocker.

Valsartan: Angiotensin II type 1 receptor blocker.

Pharmacokinetics

Half-life: Candesartan — 9 hours; Valsartan — 6 hours.

Chemical Properties

Molecular Formula: Candesartan — C33H34N6O6; Valsartan — C24H29N5O3.

Molecular Weight: Candesartan — 610.6640 g/mol; Valsartan — 435.5190 g/mol.

Type: Candesartan — Small molecule; Valsartan — Small molecule.