Captopril vs Citalopram

Captopril vs Citalopram: Overview

This comparison examines the pharmacological differences between Captopril and Citalopram.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Citalopram: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Citalopram — 35 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Citalopram — C20H21FN2O.

Molecular Weight: Captopril — 217.2850 g/mol; Citalopram — 324.3920 g/mol.

Type: Captopril — Small molecule; Citalopram — Small molecule.