Captopril vs Metoprolol

Captopril vs Metoprolol: Overview

This comparison examines the pharmacological differences between Captopril and Metoprolol.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Metoprolol: Selective beta-1 adrenergic receptor blocker.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Metoprolol — 3-7 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Metoprolol — C15H25NO3.

Molecular Weight: Captopril — 217.2850 g/mol; Metoprolol — 267.3640 g/mol.

Type: Captopril — Small molecule; Metoprolol — Small molecule.