Captopril vs Metoprolol

## Captopril vs Metoprolol: Overview

This comparison examines the pharmacological differences between **Captopril** and **Metoprolol**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Metoprolol**: Selective beta-1 adrenergic receptor blocker.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Metoprolol — 3-7 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Metoprolol — C15H25NO3.

**Molecular Weight**: Captopril — 217.2850 g/mol; Metoprolol — 267.3640 g/mol.

**Type**: Captopril — Small molecule; Metoprolol — Small molecule.