Captopril vs Montelukast

Captopril vs Montelukast: Overview

This comparison examines the pharmacological differences between Captopril and Montelukast.

Mechanism of Action

Captopril: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Montelukast: Selective leukotriene D4 receptor antagonist.

Pharmacokinetics

Half-life: Captopril — 1.9 hours; Montelukast — 2.7-5.5 hours.

Chemical Properties

Molecular Formula: Captopril — C9H15NO3S; Montelukast — C35H36ClNO3S.

Molecular Weight: Captopril — 217.2850 g/mol; Montelukast — 586.1800 g/mol.

Type: Captopril — Small molecule; Montelukast — Small molecule.